BDBM50365033 CHEMBL1950904

SMILES COc1ccc(cc1)C1CN(CCO1)c1cc(ncn1)N1CCC[C@H]1c1nc2cc(Cl)c(Cl)cc2[nH]1

InChI Key InChIKey=TVRVKXWQZDQWCS-NQCNTLBGSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50365033   

TargetLysosomal Pro-X carboxypeptidase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50365033(CHEMBL1950904)
Affinity DataIC50:  21nMAssay Description:Inhibition of human recombinant PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate after 30 mins by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysosomal Pro-X carboxypeptidase(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50365033(CHEMBL1950904)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of mouse recombinant PrCP assessed as angiotensin 3 cleavage after 8 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysosomal Pro-X carboxypeptidase(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50365033(CHEMBL1950904)
Affinity DataIC50:  46nMAssay Description:Inhibition of mouse recombinant PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate after 30 mins by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed