BDBM50365805 CHEMBL1956880

SMILES Cc1cccc(c1)-c1nc(Nc2ccc(cc2)C(O)=O)c2ccccc2n1

InChI Key InChIKey=GRHVGELKFLMPKV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50365805   

TargetMitogen-activated protein kinase 14(Human)
Sejong University

Curated by ChEMBL
LigandPNGBDBM50365805(CHEMBL1956880)
Affinity DataIC50: 2.04E+4nMAssay Description:Inhibition of MAPK p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50365805(CHEMBL1956880)
Affinity DataKi:  5.66E+4nMAssay Description:Allosteric inhibition of N-terminal his6-tagged human recombinant RORgamma LBD (261 to 518 residues) expressed in Sf9 insect cells assessed as inhibi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50365805(CHEMBL1956880)
Affinity DataIC50: 1.08E+5nMAssay Description:Allosteric inhibition of N-terminal his6-tagged human recombinant RORgamma LBD (261 to 518 residues) expressed in Sf9 insect cells incubated for 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed