BDBM50368389 CHEMBL4174412

SMILES COc1cccc(Nc2nc(nc3ccc(cc23)[N+]([O-])=O)-c2cccnc2)c1

InChI Key InChIKey=ZBRTWSUCWFIGDC-UHFFFAOYSA-N

Data  1 IC50  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50368389   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50368389(CHEMBL4174412)Copy SMILESCopy InChI

Affinity DataIC50: 47nMAssay Description:Inhibition of c-terminal GFP-tagged human ABCG2 expressed in MDCK2 cells preincubated for 30 mins before Hoechst 33342 addition by Hoechst 33342 accu...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/14/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50368389(CHEMBL4174412)Copy SMILESCopy InChI

Affinity DataEC50:  690nMAssay Description:Activation of ATPase activity of ABCG2 (unknown origin) expressed in High Five insect cell membranes by ascorbic acid ammonia molybdate reaction base...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/14/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL