BDBM50368866 CHEMBL4159656

SMILES CC1=C(c2cccc(O)c2)[C@@H](c2ccc(OC[C@H](C)N3CC[C@@H](C)C3)cc2)Oc2ccc(O)cc21

InChI Key InChIKey=JPFFAEPFVTWVBI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50368866   

TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368866BDBM50368866(CHEMBL4159656)
Affinity DataIC50: 9.70nMAssay Description:Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal dextran-treated FBS incubated for 4 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368866BDBM50368866(CHEMBL4159656)
Affinity DataIC50: 9.70nMAssay Description:Induction of ERalpha degradation in human MCF7 cells assessed as decrease in ERalpha protein level after 4 hrs by InCell Western assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368866BDBM50368866(CHEMBL4159656)
Affinity DataIC50: 136nMAssay Description:Binding affinity to ERalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed