BDBM50369336 CHEMBL1237306

SMILES C[C@]12CC=C3[C@@H](CCC4=CC(=O)CCN34)C1CCC2=O

InChI Key InChIKey=RGWYPOLINDNTEZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50369336   

Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50369336(CHEMBL1237306)
Affinity DataIC50: 4.10nMAssay Description:Inhibition against 5 alpha R-2 in human prostate homogenate relative to finasterideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50369336(CHEMBL1237306)
Affinity DataIC50: 263nMAssay Description:Inhibitory activity against human 5-alpha Reductase-1 expressed in DU-145 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50369336(CHEMBL1237306)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibitory activity against 5-alpha Reductase-2 on human prostate homogenates from surgically derived benign hyperplastic tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50369336(CHEMBL1237306)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibitory activity against 5-alpha Reductase-2 on human prostate homogenates from surgically derived benign hyperplastic tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed