BDBM50369364 CHEMBL1790760

SMILES CC[C@@H](C)[C@@H](CN(CC(=O)N[C@@H](CCSC)C(O)=O)Cc1ccccc1)NCCCS

InChI Key InChIKey=HCAOKPQDIXSPIN-HLAWJBBLSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50369364   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL

LigandBDBM50369364(CHEMBL1790760)Copy SMILESCopy InChI

Affinity DataIC50:  2.20nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant human Ha-Ras by FarnesyltransferaseMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetGeranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Bovine)
Merck Research Laboratories

Curated by ChEMBL

LigandBDBM50369364(CHEMBL1790760)Copy SMILESCopy InChI

Affinity DataIC50:  3.90E+4nMAssay Description:Inhibition of bovine Geranylgeranyl transferase type IMore data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI