BDBM50369371 CHEMBL1790750

SMILES CC[C@@H](C)[C@@H](CN(CC(=O)N[C@@H](CCO)C(O)=O)Cc1cccc2ccccc12)NC[C@@H](N)CS

InChI Key InChIKey=RZBJVSPOAOKUHC-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50369371   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL

LigandBDBM50369371(CHEMBL1790750)Copy SMILESCopy InChI

Affinity DataIC50: 0.123nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant human Ha-Ras by FarnesyltransferaseMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLKEGGPC cidPC sidSimilars

In Depth
Date in BDB:
11/7/2012
Entry Details Article
Copy Entry DOIPubMed
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TargetGeranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Bovine)
Merck Research Laboratories

Curated by ChEMBL

LigandBDBM50369371(CHEMBL1790750)Copy SMILESCopy InChI

Affinity DataIC50: 10nMAssay Description:Inhibition of bovine Geranylgeranyl transferase type IMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLKEGGPC cidPC sidSimilars

In Depth
Date in BDB:
11/7/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL