BDBM50370092 CHEMBL309617

SMILES Cc1c(F)c(Oc2cccc(c2)C(N)=N)nc(Oc2cccc(c2)-n2ccnc2)c1F

InChI Key InChIKey=ZPNZRLKRYUKJLI-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50370092   

TargetCoagulation factor X(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50370092(CHEMBL309617)
Affinity DataKi:  125nMAssay Description:Inhibitory constant against human coagulation factor Xa (fXa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50370092(CHEMBL309617)
Affinity DataKi:  4.80E+3nMAssay Description:Inhibitory constant against bovine trypsin for general specificity against serine proteasesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50370092(CHEMBL309617)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibitory constant against human coagulation factor II (thrombin) for selectivity within coagulation cascadeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed