BDBM50371042 CHEMBL229212

SMILES CC(C)CCNC(=O)c1ccc(nn1)N1CCN(CC1)C(=O)c1ccccc1C(F)(F)F

InChI Key InChIKey=NGGBGFKKADSXPM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50371042   

TargetAcyl-CoA desaturase 1(Mouse)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50371042(CHEMBL229212)
Affinity DataIC50: 26nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50371042(CHEMBL229212)
Affinity DataIC50: 37nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Mouse)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50371042(CHEMBL229212)
Affinity DataIC50: 627nMAssay Description:Inhibition of SCD1 in ob/ob mouse liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed