BDBM50371562 CHEMBL271992

SMILES COc1ccc(S(=O)(=O)C=CCNC(=O)CN2C(=O)C(COC(=O)Nc3ccc(Cl)cc3C(F)(F)F)N=C(c3ccccc3)c3ccccc32)cc1

InChI Key InChIKey=HRNWFMOUQSMTQH-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50371562   

TargetFalcipain 2(malaria parasite P. falciparum)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50371562BDBM50371562(CHEMBL271992)
Affinity DataKi:  120nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetCathepsin B(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50371562BDBM50371562(CHEMBL271992)
Affinity DataKi:  5.90E+3nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetFalcipain 2(malaria parasite P. falciparum)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50371562BDBM50371562(CHEMBL271992)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of Plasmodium falciparum recombinant falcipain-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50371562BDBM50371562(CHEMBL271992)
Affinity DataKi:  1.40E+4nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed