BDBM50371768 CHEMBL427835

SMILES NS(=O)(=O)c1ccc(cc1)\N=C\c1ccc(F)cc1

InChI Key InChIKey=BKZPDMSMFWCHPI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50371768   

TargetCarbonic anhydrase 12(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50371768BDBM50371768(CHEMBL427835)
Affinity DataKi:  16nMAssay Description:Inhibition of human Nav1.7 at -60 mV holding potential by cell-based IonWorks barracuda automated electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetCarbonic anhydrase 2(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50371768BDBM50371768(CHEMBL427835)
Affinity DataKi:  49nMAssay Description:Antagonist activity at recombinant human PPARalpha assessed as inhibition of GW7647-induced receptor activation after overnight incubation by cell-ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetCarbonic anhydrase 1(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50371768BDBM50371768(CHEMBL427835)
Affinity DataKi:  136nMAssay Description:Antagonist activity at recombinant human PPARdelta assessed as inhibition of GW0742-induced receptor activation after overnight incubation by cell-ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetCarbonic anhydrase 9(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50371768BDBM50371768(CHEMBL427835)
Affinity DataKi:  216nMAssay Description:Antagonist activity at recombinant human PPARdelta assessed as inhibition of GW0742-induced receptor activation after overnight incubation by cell-ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetProstaglandin G/H synthase 2(Human)
Taipei Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50371768BDBM50371768(CHEMBL427835)
Affinity DataIC50: 2.22E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Taipei Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50371768BDBM50371768(CHEMBL427835)
Affinity DataIC50: 1.59E+5nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A-23187-stimulated TxB2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed