BDBM50372116 CHEMBL256468

SMILES Cc1oc(nc1CCOc1ccc(C[C@H]2[C@H](N(C2=O)c2ccc(cc2)C(C)(C)C)C(O)=O)cc1)-c1ccccc1

InChI Key InChIKey=HWOKKMFQJSXDKU-YTMVLYRLSA-N

Data  6 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50372116   

TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50372116(CHEMBL256468)
Affinity DataEC50:  4nMAssay Description:Agonist activity at PPARgamma in HEK293 cells by GAL4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50372116(CHEMBL256468)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of CYP3A4 in presence of 7-benzyloxy-4-trifluoromethyl coumarin substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50372116(CHEMBL256468)
Affinity DataIC50:  1.81E+4nMAssay Description:Inhibition of human ERG by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50372116(CHEMBL256468)
Affinity DataIC50:  110nMAssay Description:Inhibition of PPARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50372116(CHEMBL256468)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50372116(CHEMBL256468)
Affinity DataIC50:  790nMAssay Description:Inhibition of PPARalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50372116(CHEMBL256468)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of CYP3A4 in presence of 7-benzyloxyresorufin substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50372116(CHEMBL256468)
Affinity DataEC50:  10nMAssay Description:Agonist activity at PPARalpha in HEK293 cells by GAL4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed