BDBM50372166 CHEMBL404223

SMILES Nc1n[nH]c2nccc(-c3ccc(NC(=O)Nc4ccccc4)cc3)c12

InChI Key InChIKey=UYICFVSQIQCCIA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50372166   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50372166BDBM50372166(CHEMBL404223)
Affinity DataIC50: 4nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation in mouse 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50372166BDBM50372166(CHEMBL404223)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50372166BDBM50372166(CHEMBL404223)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of KDR kinase activity (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50372166BDBM50372166(CHEMBL404223)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of KDR kinase activity (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article