BDBM50372200 CHEMBL256434

SMILES CCCN(CCC)C(=O)c1cc(C)cc(c1)C(=O)N[C@@H](Cc1cc(F)cc(F)c1)[C@H](O)[C@H]1CCCN1

InChI Key InChIKey=QOXKSOYSLISNQZ-UODIDJSMSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50372200   

TargetBeta-secretase 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372200(CHEMBL256434)
Affinity DataIC50:  65nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50372200(CHEMBL256434)
Affinity DataIC50:  330nMAssay Description:Inhibition of human BACE1 assessed as amyloid beta 40 production in human HEK293 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed