BDBM50372749 CHEMBL4164245

SMILES Cc1oc2c(c1C(=O)Oc1cccc(c1)-c1cn(CCCO)nn1)C(=O)c1ncccc1C2=O

InChI Key InChIKey=GGOQUHIMSMXYCP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50372749   

TargetTyrosyl-DNA phosphodiesterase 2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50372749(CHEMBL4164245)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of recombinant human TDP2 using TY18 (alpha-[32P]-cordycepin-3'-labeled) as substrate after 15 mins by PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50372749(CHEMBL4164245)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of human TDP2 expressed in TDP2 deficient chicken DT40 whole cell extracts using TY19 DNA as substrate after 15 mins by by PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed