BDBM50372943 CHEMBL272789

SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)N1CCC2=Cc3c(C[C@]2(C)C1)cnn3-c1ccc(F)cc1

InChI Key InChIKey=OIKFLZJCOASDMC-HHHXNRCGSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50372943   

TargetGlucocorticoid receptor(Human)
Corcept Therapeutics

Curated by ChEMBL
LigandPNGBDBM50372943(CHEMBL272789)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]dexamethasone from human recombinant GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlucocorticoid receptor(Human)
Corcept Therapeutics

Curated by ChEMBL
LigandPNGBDBM50372943(CHEMBL272789)
Affinity DataKi:  53nMAssay Description:Antagonist activity at GR in SW1353/MMTV5 cells assessed as inhibition of dexamethasone-induced luciferase expressionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed