BDBM50373700 CHEMBL410242

SMILES C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1C[C@H](Cc1cccc(c1)C(N)=O)[C@@H]2O

InChI Key InChIKey=RSVOVHDOLNWYER-RYZVYYIHSA-N

Data  4 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50373700   

Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Chuq-Pavillon Chul And Universit£

Curated by ChEMBL
LigandPNGBDBM50373700(CHEMBL410242)
Affinity DataIC50:  44nMAssay Description:Inhibition of 17beta-HSD1 in human T47D cells assessed as inhibition of transformation of [14C]-estrone into [14C]estrogenMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Laval University

Curated by ChEMBL
LigandPNGBDBM50373700(CHEMBL410242)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Chuq-Pavillon Chul And Universit£

Curated by ChEMBL
LigandPNGBDBM50373700(CHEMBL410242)
Affinity DataIC50:  27nMAssay Description:Inhibition of 17-beta HSD1 in human T47D cells assessed as transformation of [14C]E1 to [14C]E2 after 24 hrs by thin layer chromatographyMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Chuq-Pavillon Chul And Universit£

Curated by ChEMBL
LigandPNGBDBM50373700(CHEMBL410242)
Affinity DataIC50:  27nMAssay Description:Inhibition of 17beta-HSD1 in human T47D cells assessed as decrease in transformation of [14C]estrone to [14C]-estradiol after 24 hrs by thin layer ch...More data for this Ligand-Target Pair