BDBM50374463 CHEMBL402243

SMILES COc1ccc(CC(=O)N2CCN(CC2C(C)(C)C)C(NC#N)=Nc2ccccc2C)cc1OC

InChI Key InChIKey=ITTCMJKZDOEMMP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50374463   

TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50374463(CHEMBL402243)
Affinity DataIC50:  420nMAssay Description:Antagonist activity at rat recombinant P2X7 receptor assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50374463(CHEMBL402243)
Affinity DataIC50:  190nMAssay Description:Antagonist activity at human recombinant P2X7 receptor assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed