BDBM50374620 CHEMBL407516

SMILES CN1CCN(CCOc2ccc(Nc3ncc4c(n3)n3c5ccccc5nc3n(-c3c(C)cccc3C)c4=O)cc2F)CC1

InChI Key InChIKey=ATAXRSLEVBMIFF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50374620   

TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50374620(CHEMBL407516)
Affinity DataIC50: 23nMAssay Description:Inhibition of Lck by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50374620(CHEMBL407516)
Affinity DataIC50: 160nMAssay Description:Inhibition of Src by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50374620(CHEMBL407516)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50374620(CHEMBL407516)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p38-alpha by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed