BDBM50375124 CHEMBL256457

SMILES CN(CCCn1c2c(Cl)cccc2n(CC(=O)c2ccc(Cl)cc2)c1=N)C(=O)c1ccc2ccccc2c1

InChI Key InChIKey=JHKADHPONGIEOY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50375124   

TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50375124(CHEMBL256457)
Affinity DataIC50:  15nMAssay Description:Displacement of [125I]-CXCL10 from human CXCR3 expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Mus musculus)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50375124(CHEMBL256457)
Affinity DataIC50:  500nMAssay Description:Displacement of [125I]-CXCL10 from mouse CXCR3 expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50375124(CHEMBL256457)
Affinity DataIC50:  40nMAssay Description:Antagonist activity at human CXCR3 expressed in CHO cell membrane assessed as inhibition of calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed