BDBM50375584 CHEMBL429432

SMILES C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4CCCC[C@]4(C)[C@H]3CC[C@]12C

InChI Key InChIKey=RPKLZQLYODPWTM-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50375584   

TargetAldo-keto reductase family 1 member B10(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50375584BDBM50375584(CHEMBL429432)
Affinity DataIC50: 50nMAssay Description:Inhibition of AKR1B10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetPresenilin-1(Human)
Banaras Hindu University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50375584BDBM50375584(CHEMBL429432)
Affinity DataIC50: 5.68E+3nMAssay Description:Inverse modulatory activity at gamma-secretase (unknown origin) assessed as increase in amyloid beta (1 to 42) levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Banaras Hindu University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50375584BDBM50375584(CHEMBL429432)
Affinity DataEC50:  5.70E+3nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human APP695 assessed as inhibition of amyloid beta 42 production after 16 hrs by sandwich...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50375584BDBM50375584(CHEMBL429432)
Affinity DataEC50:  6.08E+3nMAssay Description:Agonist activity at human TGR5 expressed in CHO cells by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50375584BDBM50375584(CHEMBL429432)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of AKR1B1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed