BDBM50375605 CHEMBL258738

SMILES OC(=O)Cc1ccccc1Nc1c(Cl)cccc1C(F)(F)F

InChI Key InChIKey=ZIDKZLBDQFHPQK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50375605   

TargetProstaglandin G/H synthase 2(Human)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375605(CHEMBL258738)
Affinity DataIC50: 166nMAssay Description:Inhibition of human COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375605(CHEMBL258738)
Affinity DataIC50: 241nMAssay Description:Inhibition of mouse COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375605(CHEMBL258738)
Affinity DataIC50: 696nMAssay Description:Inhibition of ovine COX1 for 17 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed