BDBM50375809 CHEMBL429347

SMILES [#6]-[#6@@H](-[#6]-[#6@@H]-1-[#6]-[#6](=[#6])-[#6](=O)-[#8]-1)-[#6@H]1-[#6]-[#6]-[#6@H]2\[#6](-[#6]-[#6]-[#6][C@]12[#6])=[#6]\[#6]=[#6]-1\[#6]-[#6@@H](-[#8])-[#6](=[#6])-[#6@H](-[#8])-[#6]-1

InChI Key InChIKey=NFEAURPDDCSCJD-IBPQAKBISA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50375809   

TargetVitamin D3 receptor(Rat)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50375809(CHEMBL429347)
Affinity DataEC50:  5nMAssay Description:Displacement of [3H]1,25-(OH)2D3 from rat recombinant His-tagged VDR ligand-binding domain expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Human)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50375809(CHEMBL429347)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human VDR in HEK293 cells assessed as induction of transcriptional transactivation after 24 hrs by mouse osteopontin luciferase r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Human)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50375809(CHEMBL429347)
Affinity DataIC50:  300nMAssay Description:Antagonist activity at human VDR in COS7 cells assessed as induction of transcriptional transactivation after 24 hrs by mouse osteopontin luciferase ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Human)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandPNGBDBM50375809(CHEMBL429347)
Affinity DataEC50:  6nMAssay Description:Agonist activity at human VDR in COS7 cells assessed as induction of transcriptional transactivation after 24 hrs by mouse osteopontin luciferase rep...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed