BDBM50375809 CHEMBL429347

SMILES C=C1C[C@@H](C[C@H](C)[C@H]2CC[C@H]3/C(=C/C=C4C[C@@H](O)C(=C)[C@H](O)C4)CCC[C@]23C)OC1=O

InChI Key InChIKey=TVQCSHDUZNHJQU-UHFFFAOYSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50375809   

TargetVitamin D3 receptor(Rat)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50375809BDBM50375809(CHEMBL429347)
Affinity DataEC50:  5nMAssay Description:Displacement of [3H]1,25-(OH)2D3 from rat recombinant His-tagged VDR ligand-binding domain expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50375809BDBM50375809(CHEMBL429347)
Affinity DataEC50:  6nMAssay Description:Agonist activity at human VDR in COS7 cells assessed as induction of transcriptional transactivation after 24 hrs by mouse osteopontin luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50375809BDBM50375809(CHEMBL429347)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human VDR in HEK293 cells assessed as induction of transcriptional transactivation after 24 hrs by mouse osteopontin luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
Tokyo Medical and Dental University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50375809BDBM50375809(CHEMBL429347)
Affinity DataIC50: 300nMAssay Description:Antagonist activity at human VDR in COS7 cells assessed as induction of transcriptional transactivation after 24 hrs by mouse osteopontin luciferase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed