BDBM50378541 CHEMBL570321

SMILES CCOC(=O)CN1C(=O)S\C(=C/c2ccc(o2)-c2ccc(Cl)c(c2)C(O)=O)C1=O

InChI Key InChIKey=UIPUZDWBISFWKB-NVNXTCNLSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50378541   

TargetIntegrin alpha-M/beta-2(Human)
Department of Medicine and University of Miami

Curated by ChEMBL
LigandPNGBDBM50378541(CHEMBL570321)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at CD11b/CD18 expressed in K562 cells assessed as increase in cell adhesion to fibrinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50378541(CHEMBL570321)
Affinity DataIC50: <3.16E+5nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 5 mins by liquid scintillation counting ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50378541(CHEMBL570321)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 5 mins by liquid scintillation counting ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 3(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50378541(CHEMBL570321)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 5 mins by liquid scintillation counting ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50378541(CHEMBL570321)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 5 mins by liquid scintillation counting ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed