BDBM50378763 CHEMBL1204077

SMILES On1cc(C2CCNCC2)c(n1)-c1cccc(c1)-c1ccccc1

InChI Key InChIKey=ZGEMNNHBINYTKL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50378763   

TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50378763(CHEMBL1204077)
Affinity DataIC50: 210nMAssay Description:Antagonist activity at human alpha1beta2gamma2S GABA-A receptor expressed in tsA201 cells assessed as inhibition of GABA-induced effect after 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50378763(CHEMBL1204077)
Affinity DataIC50: 210nMAssay Description:Antagonist activity at human alpha1beta2gamma2S GABA(A) receptor expressed in human tsA201 cells assessed as inhibition of GABA-induced membrane pote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50378763(CHEMBL1204077)
Affinity DataIC50: 210nMAssay Description:Antagonist activity at human GABAA alpha-1-beta-2-gamma-2 receptor expressed in mouse tsA201 cells by FMP red assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed