BDBM50378915 CHEMBL6133434

SMILES O=C1CCc2cccc(Oc3nc(Nc4ccc(N5CCN(C(=S)SCCCN6CCOCC6)CC5)cc4)ncc3C(F)(F)F)c21

InChI Key InChIKey=NEGJJUZTNLUJIX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50378915   

TargetFocal adhesion kinase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378915BDBM50378915(CHEMBL6133434)
Affinity DataIC50: 45nMAssay Description:Inhibition of FLT3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetFocal adhesion kinase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378915BDBM50378915(CHEMBL6133434)
Affinity DataIC50: 45nMAssay Description:Inhibition of TACE by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMed
TargetInsulin receptor(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378915BDBM50378915(CHEMBL6133434)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of VEGFR3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details
PubMed
TargetInsulin receptor(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378915BDBM50378915(CHEMBL6133434)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of FLT3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed