BDBM50378972 CHEMBL2011249::US9394290, 18

SMILES Cc1ccc(cc1N)-c1ccc(Cn2ccnc2)cn1

InChI Key InChIKey=QBKHQFWUGYDJIC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50378972   

TargetCytochrome P450 11B1, mitochondrial(Human)
Universitaet Des Saarlandes Campus Saarbruecken

US Patent
LigandPNGBDBM50378972(CHEMBL2011249 | US9394290, 18)
Affinity DataIC50:  542nMT: 37°CAssay Description:V79MZ cells expressing human CYP11B1 and human CYP11B2 genes, respectively, were grown on 24-well cell culture plates (8×10^5 cells per well) w...More data for this Ligand-Target Pair
In DepthDetails US Patent


LigandPNGBDBM50378972(CHEMBL2011249 | US9394290, 18)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 11B1, mitochondrial(Human)
Universitaet Des Saarlandes Campus Saarbruecken

US Patent
LigandPNGBDBM50378972(CHEMBL2011249 | US9394290, 18)
Affinity DataIC50:  542nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZ cells using [3H] 11 deoxycorticosterone as substrate by HPLC radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50378972(CHEMBL2011249 | US9394290, 18)
Affinity DataIC50: >1.00E+3nMT: 37°CAssay Description:V79MZ cells expressing human CYP11B1 and human CYP11B2 genes, respectively, were grown on 24-well cell culture plates (8×10^5 cells per well) w...More data for this Ligand-Target Pair
In DepthDetails US Patent