BDBM50379431 CHEMBL2012178

SMILES Cc1c(C)c2c(OC3CCN(Cc4cscn4)CC3)ncnc2n1Cc1ccccc1

InChI Key InChIKey=AKEOVDDAHTWBGN-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50379431   

LigandPNGBDBM50379431(CHEMBL2012178)
Affinity DataKi:  2.50E+3nMAssay Description:Displacement of dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50379431(CHEMBL2012178)
Affinity DataIC50:  120nMAssay Description:Antagonist activity at human NaV1.5 channel by patchXpress assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50379431(CHEMBL2012178)
Affinity DataIC50:  150nMAssay Description:Antagonist activity at human NaV1.7 channel by patchXpress assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50379431(CHEMBL2012178)
Affinity DataIC50:  6.40E+3nMAssay Description:Antagonist activity at human NaV1.7 channel by electrophysiology-based screening assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50379431(CHEMBL2012178)
Affinity DataIC50:  510nMAssay Description:Inhibition of human ERG by patchXpress assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50379431(CHEMBL2012178)
Affinity DataIC50:  60nMAssay Description:Antagonist activity at 20% inactivated human NaV1.7 channel by electrophysiology-based screening assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed