BDBM50379560 CHEMBL2012881

SMILES O=c1[nH]nc2cc(CO)c3ccc(-c4ccc[nH]4)cc3n12

InChI Key InChIKey=FEKDFTQZRBQDGS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50379560   

TargetSerine/threonine-protein kinase Chk1(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379560BDBM50379560(CHEMBL2012881)
Affinity DataIC50: 20nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379560BDBM50379560(CHEMBL2012881)
Affinity DataIC50: 319nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379560BDBM50379560(CHEMBL2012881)
Affinity DataIC50: 650nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50379560BDBM50379560(CHEMBL2012881)
Affinity DataIC50: 650nMAssay Description:Inhibition of MAP3K7More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed