BDBM50380277 CHEMBL2017244

SMILES COCCNc1ncnc2c(Nc3ccccc3SC)nc(nc12)N1CCNCC1

InChI Key InChIKey=HLBHCLSWXWEMKG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50380277   

TargetKetohexokinase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50380277(CHEMBL2017244)
Affinity DataIC50:  7nMAssay Description:Inhibition of human ketohexokinase isoform C expressed in Escherichia coli BL21 (DE3) cells using D-fructose as substrate after 12 to 15 mins by fluo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKetohexokinase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50380277(CHEMBL2017244)
Affinity DataIC50:  140nMAssay Description:Inhibition of ketokinase isoform C in human HepG2 cells assessed as levels of fructose-1-phosphate preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed