BDBM50380290 CHEMBL2017444

SMILES Clc1ccc(-c2ccc(o2)C(=O)Nc2ccc(cc2)N2CCNCC2)c(Cl)c1

InChI Key InChIKey=GJQZQVRIRSQPIP-UHFFFAOYSA-N

Data  1 IC50  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50380290   

TargetMAP kinase-activated protein kinase 2(Human)
TBA

Curated by ChEMBL

LigandBDBM50380290(CHEMBL2017444)Copy SMILESCopy InChI

Affinity DataEC50:  1.60E+3nMAssay Description:Inhibition of MK2-mediated HSP27 phosphorylation in IL-1beta stimulated human SW1353 cells incubated for 30 mins prior to IL-1beta-stimulation measur...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
Entry Details Article
Copy BDB DOIPubMed
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TargetMAP kinase-activated protein kinase 2(Human)
TBA

Curated by ChEMBL

LigandBDBM50380290(CHEMBL2017444)Copy SMILESCopy InChI

Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of MK2 using Acam peptide as substrate incubated for 30 mins prior to substrate addition measured after 10 mins using 100 uM ATP by DELFIA...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL