BDBM50380296 CHEMBL2017450

SMILES FC(F)(F)c1cc(ccc1NC(=O)c1ccc(o1)-c1ccc(Cl)cc1)N1CCNCC1

InChI Key InChIKey=XMDGCSWRCZWUON-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50380296   

LigandPNGBDBM50380296(CHEMBL2017450)
Affinity DataEC50: >8.00E+3nMAssay Description:Inhibition of MK2-mediated HSP27 phosphorylation in IL-1beta stimulated human SW1353 cells incubated for 30 mins prior to IL-1beta-stimulation measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50380296(CHEMBL2017450)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of MK2 using Acam peptide as substrate incubated for 30 mins prior to substrate addition measured after 10 mins using 100 uM ATP by DELFIA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed