BDBM50380627 CHEMBL2016875

SMILES NC(=N)c1ccc(CNC(=O)[C@@H]2Cc3cn(CC4=CCC=C(Cn5cc(C[C@@H](NS(=O)(=O)Cc6ccccc6)C(=O)N2)nn5)N4O)nn3)cc1

InChI Key InChIKey=KOFPLCRLJGKZIC-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50380627   

TargetPlasminogen(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50380627(CHEMBL2016875)
Affinity DataKi:  8.90nMAssay Description:Inhibition of plasmin by dixon plot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50380627(CHEMBL2016875)
Affinity DataKi:  67nMAssay Description:Inhibition of plasma kallikrein by dixon plot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProthrombin(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50380627(CHEMBL2016875)
Affinity DataKi:  1.18E+3nMAssay Description:Inhibition of thrombin by dixon plot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50380627(CHEMBL2016875)
Affinity DataKi:  3.12E+3nMAssay Description:Inhibition of factor 10a by dixon plot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetVitamin K-dependent protein C(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50380627(CHEMBL2016875)
Affinity DataKi: >6.00E+3nMAssay Description:Inhibition of activated protein C by dixon plot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed