BDBM50380642 CHEMBL2017066

SMILES COc1cc2CCn3cnc(-c4cnc(CN5CCOCC5)s4)c3-c2cc1OC

InChI Key InChIKey=YQQZBBVGXNRWDB-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50380642   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50380642(CHEMBL2017066)
Affinity DataKi:  6.60nMAssay Description:Inhibition of human recombinant PDE10A assessed as inhibition of [3H]cAMP hydrolysis by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50380642(CHEMBL2017066)
Affinity DataKi:  148nMAssay Description:Inhibition of human recombinant PDE3A assessed as inhibition of [3H]cAMP hydrolysis by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50380642(CHEMBL2017066)
Affinity DataKi:  4.60E+3nMAssay Description:Inhibition of human recombinant PDE7A1 assessed as inhibition of [3H]cAMP hydrolysis by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed