BDBM50380866 CHEMBL2018967

SMILES COc1cccc2n(Cc3cccc(CNC(=O)CO)c3)nc(NS(=O)(=O)c3ccc(Cl)s3)c12

InChI Key InChIKey=BVOPWMBIOVEEKK-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50380866   

TargetC-C chemokine receptor type 4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50380866(CHEMBL2018967)
Affinity DataKi:  15.8nMAssay Description:Displacement of [125I]TARC from human CCR4 expressed in CHO membranes by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-C chemokine receptor type 4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50380866(CHEMBL2018967)
Affinity DataIC50:  27.5nMAssay Description:Antagonist activity at human CCR4 expressed in CHO membranes assessed as inhibition of [35S]-GTPgammaS binding by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC-C chemokine receptor type 4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50380866(CHEMBL2018967)
Affinity DataKd:  2.00E+3nMAssay Description:Antagonist activity at human CCR4 in human whole blood assessed as inhibition of TARC-induced CD4+ CCR4+lymphocyte chemotaxis measuring F-actin conte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed