BDBM50381090 CHEMBL2017551

SMILES CCOc1cc2[nH]c(-c3n[nH]cc3NC(=O)N(CC)CC)nc2cc1F

InChI Key InChIKey=UJXIKUVGGQECLJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50381090   

TargetTyrosine-protein kinase SYK(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50381090BDBM50381090(CHEMBL2017551)
Affinity DataIC50: 8nMAssay Description:Inhibition of SYK (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition measured after 25 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Second Military Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50381090BDBM50381090(CHEMBL2017551)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Syk (343 to 635) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Sanofi Us

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50381090BDBM50381090(CHEMBL2017551)
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Itk (357-620) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed