BDBM50381264 CHEMBL1235825

SMILES CN(CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12

InChI Key InChIKey=JISVTSUBJCPLSV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50381264   

TargetDNA (cytosine-5)-methyltransferase 1(Human)
University of Southampton

Curated by ChEMBL
LigandPNGBDBM50381264(CHEMBL1235825)
Affinity DataIC50: 3.02E+5nMAssay Description:Inhibition of human Dnmt1 using oligonucleotide 2 as substrate after 5000 sec by micro plate reader based real-time break-light assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50381264(CHEMBL1235825)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of recombinant NNMT (unknown origin) assessed as reduction in MNA concentration incubated for 10 mins measured after 30 mins by LC-MS/MS-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed