BDBM50382440 CHEMBL2023348

SMILES CN(C)S(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(cc2)N2CCN(C)CC2)ncc1Cl

InChI Key InChIKey=DUVYKNYFBDYPNC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50382440   

TargetSerine/threonine-protein kinase Nek2(Human)
Institute of Respiratory Healthand

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50382440BDBM50382440(CHEMBL2023348)
Affinity DataIC50: 40nMAssay Description:Inhibition of human NEK2 by Kinase-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50382440BDBM50382440(CHEMBL2023348)
Affinity DataIC50: 1.73E+3nMAssay Description:Inhibition of human recombinant His-tagged AXL kinase using fluorescein-labelled poly-GT as substrate after 60 mins by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed