BDBM50382548 CHEMBL2022995

SMILES Cc1cccc(c1)C(CC[C@H](N)C(O)=O)(c1ccccc1)c1ccccc1

InChI Key InChIKey=JXIGVUPYYZGRRZ-QFIPXVFZSA-N

Data  2 KI  6 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50382548   

TargetKinesin-like protein KIF11(Human)
The Beatson Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50382548(CHEMBL2022995)
Affinity DataKi:  11.1nMAssay Description:Inhibition of N-terminal hexa-histidine tagged human cloned Eg5 (1 to 368 amino acids) expressed in Escherichia coli BL21 (DE3) assessed as reduction...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetKinesin-like protein KIF11(Human)
The Beatson Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50382548(CHEMBL2022995)
Affinity DataKi:  12.8nMAssay Description:Inhibition of N-terminal hexa-histidine tagged human cloned Eg5 (1 to 368 amino acids) expressed in Escherichia coli BL21 (DE3) assessed as reduction...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetCytochrome P450 2C19(Human)
The Beatson Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50382548(CHEMBL2022995)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2D6(Human)
The Beatson Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50382548(CHEMBL2022995)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 3A4(Human)
The Beatson Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50382548(CHEMBL2022995)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 1A2(Human)
The Beatson Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50382548(CHEMBL2022995)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Beatson Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50382548(CHEMBL2022995)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2C9(Human)
The Beatson Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50382548(CHEMBL2022995)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed