BDBM50383116 CHEMBL2031736

SMILES Cc1c(NC(=O)c2ccc(cc2)-c2ccc(Cl)cc2)ccc2cc(CN3CCCC3)cnc12

InChI Key InChIKey=MCELKHDTMQZQBB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50383116   

TargetMelanin-concentrating hormone receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50383116(CHEMBL2031736)
Affinity DataIC50:  0.360nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50383116(CHEMBL2031736)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]mesulergine from human 5HT2C receptor expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50383116(CHEMBL2031736)
Affinity DataIC50:  7.60nMAssay Description:Antagonist activity at human MCHR1 expressed in CHO cells assessed as inhibition of MCH-induced [3H]arachidonic acid release after 16 hrs by liquid s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed