BDBM50383864 CHEMBL2031163

SMILES OC(=O)[C@H](Cc1ccc(cc1)C(=O)NCc1ccc2CCCNc2n1)NC(=O)c1c(Cl)cccc1Cl

InChI Key InChIKey=QKJVOACJWLIFLA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50383864   Sort by

TargetIntegrin alpha-V/beta-3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50383864(CHEMBL2031163)
Affinity DataIC50: 350nMAssay Description:Antagonist activity at integrin alphavbeta3 in human A375M cells assessed as inhibition of cell adhesion to fibrinogen in presence of Mg2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50383864(CHEMBL2031163)
Affinity DataIC50: 1.40E+3nMAssay Description:Antagonist activity at integrin alpha5beta1 in human A375M cells assessed as inhibition of cell adhesion to fibronectin in presence of Mg2+ and MK-04...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50383864(CHEMBL2031163)
Affinity DataIC50: 5nMAssay Description:Binding affinity to integrin alpha5beta1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50383864(CHEMBL2031163)
Affinity DataIC50: 120nMAssay Description:Antagonist activity at integrin alpha5beta1 in human K562 cells assessed as inhibition of cell adhesionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed