BDBM50383866 CHEMBL2031174

SMILES COc1ccc(cn1)[C@H](CC(O)=O)N1CCN(CCCc2ccc3CCCNc3n2)C1

InChI Key InChIKey=LSAHZFHCOBEICB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50383866   Sort by

TargetIntegrin alpha-V/beta-3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50383866(CHEMBL2031174)
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity at integrin alphavbeta3 in human A375M cells assessed as inhibition of cell adhesion to fibrinogen in presence of Mg2+More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50383866(CHEMBL2031174)
Affinity DataIC50: 2.20E+3nMAssay Description:Antagonist activity at integrin alpha5beta1 in human A375M cells assessed as inhibition of cell adhesion to fibronectin in presence of Mg2+ and MK-04...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50383866(CHEMBL2031174)
Affinity DataIC50: 4.60E+3nMAssay Description:Antagonist activity at integrin alpha5beta1 in human K562 cells assessed as inhibition of cell adhesionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed