BDBM50384954 CHEMBL2037521

SMILES C(CCc1nc2ccccc2s1)CN1CCN(CC1)c1ncccn1

InChI Key InChIKey=LOWWSZHAZVDMAY-UHFFFAOYSA-N

Data  12 KI  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50384954   

TargetD(4) dopamine receptor(Rat)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50384954(CHEMBL2037521)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(4) dopamine receptor(Rat)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50384954(CHEMBL2037521)
Affinity DataKi:  0.840nMAssay Description:Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by PDSP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(4) dopamine receptor(Human)
High Point University

Curated by ChEMBL
LigandPNGBDBM50384954(CHEMBL2037521)
Affinity DataKi:  3.10nMAssay Description:Displacement of [3H]N-methylspiperone from human D4 receptor stably expressed in HEK293 cell membrane assessed as inhibition constant incubated for 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50384954(CHEMBL2037521)
Affinity DataKi:  6.60nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50384954(CHEMBL2037521)
Affinity DataKi:  26.5nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50384954(CHEMBL2037521)
Affinity DataKi:  27nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by PDSP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(3) dopamine receptor(Human)
High Point University

Curated by ChEMBL
LigandPNGBDBM50384954(CHEMBL2037521)
Affinity DataKi:  93nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor stably expressed in HEK293 cell membrane assessed as inhibition constant incubated for 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(3) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50384954(CHEMBL2037521)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor by PDSP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50384954(CHEMBL2037521)
Affinity DataKi:  127nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 receptor stably expressed in HEK293 cell membrane assessed as inhibition constant incubated for 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2A(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50384954(CHEMBL2037521)
Affinity DataKi:  224nMAssay Description:Displacement of [3H]Ketanserin from human 5HT2A receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50384954(CHEMBL2037521)
Affinity DataKi:  229nMAssay Description:Displacement of [3H]LSD from human 5HT7 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2C(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50384954(CHEMBL2037521)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human 5HT2C receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(3) dopamine receptor(Human)
High Point University

Curated by ChEMBL
LigandPNGBDBM50384954(CHEMBL2037521)
Affinity DataEC50:  39nMAssay Description:Agonist activity at human D3 receptor stably expressed in CHO-K1 cells assessed as beta arrestin recruitment preincubated for 90 mins by tropix-gal s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(3) dopamine receptor(Human)
High Point University

Curated by ChEMBL
LigandPNGBDBM50384954(CHEMBL2037521)
Affinity DataIC50:  1.44E+3nMAssay Description:Antagonist activity at human D3 receptor stably expressed in CHO-K1 cells assessed as beta arrestin recruitment preincubated for 90 mins by tropix-ga...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50384954(CHEMBL2037521)
Affinity DataIC50:  242nMAssay Description:Antagonist activity at human D2 receptor stably expressed in CHO-K1 cells assessed as beta arrestin recruitment preincubated for 90 mins by tropix-ga...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(4) dopamine receptor(Human)
High Point University

Curated by ChEMBL
LigandPNGBDBM50384954(CHEMBL2037521)
Affinity DataIC50:  19nMAssay Description:Antagonist activity at human D4 receptor stably expressed in CHO-K1 cells assessed as beta arrestin recruitment preincubated for 90 mins by tropix-ga...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50384954(CHEMBL2037521)
Affinity DataIC50:  353nMAssay Description:Antagonist activity at human D2 receptor stably expressed in CHO-K1 cells assessed as inhibition of forskolin stimulated cAMP production incubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(4) dopamine receptor(Human)
High Point University

Curated by ChEMBL
LigandPNGBDBM50384954(CHEMBL2037521)
Affinity DataIC50:  32nMAssay Description:Antagonist activity at human D4 receptor stably expressed in CHO-K1 cells assessed as inhibition of forskolin stimulated cAMP production incubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed