BDBM50385071 CHEMBL2035621

SMILES Fc1ccc(Cl)c(c1)-c1nc2c3cc(Br)ccc3oc2c(=O)[nH]1

InChI Key InChIKey=LVKVPSJZKQLBMV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50385071   

TargetSerine/threonine-protein kinase pim-1(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50385071(CHEMBL2035621)
Affinity DataIC50:  14nMAssay Description:Inhibition of N-terminal His-tagged human PIM1 expressed in Escherichia coli using AKRRRLSA as substrate after 1 to 2 hrs by luciferasse-luciferin-co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50385071(CHEMBL2035621)
Affinity DataIC50:  13nMAssay Description:Inhibition of N-terminal His-tagged human PIM3 expressed in Escherichia coli using AKRRRLSA as substrate after 1 to 2 hrs by luciferasse-luciferin-co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50385071(CHEMBL2035621)
Affinity DataIC50:  653nMAssay Description:Inhibition of N-terminal His-tagged human PIM2 expressed in Escherichia coli using AKRRRLSA as substrate after 1 to 2 hrs by luciferasse-luciferin-co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed