BDBM50386387 CHEMBL2046875

SMILES CCOc1ccc(Cc2nc3cc(ccc3n2C2CCN(C)CC2)N=C(N)c2cccs2)cc1

InChI Key InChIKey=GNFYBQQYKYATIJ-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50386387   

TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50386387(CHEMBL2046875)
Affinity DataKi:  2.90E+3nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK-293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50386387(CHEMBL2046875)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human recombinant eNOS assessed as conversion of [3H]L-arginine to [3H]L-citrulline preincubated for 15 mins measured after 45 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50386387(CHEMBL2046875)
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibition of human recombinant nNOS assessed as conversion of [3H]L-arginine to [3H]L-citrulline preincubated for 15 mins measured after 45 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed