BDBM50386404 CHEMBL1332325

SMILES CCC(=O)Nc1cccc(NC(=O)c2ccccc2Br)c1

InChI Key InChIKey=MRHAVVLJBCSEMH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50386404   

TargetProteinase-activated receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50386404(CHEMBL1332325)
Affinity DataIC50:  1.68E+3nMAssay Description:Inhibition of SFLLRN-NH2-stimulated PAR1-mediated platelet activation in platelet-rich human plasma assessed as surface expression of P-selectin afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProteinase-activated receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50386404(CHEMBL1332325)
Affinity DataIC50:  3.16E+3nMAssay Description:Negative allosteric modulation of PAR1 in human EAhy926 cells assessed as reduction in TFLLRN-NH2-induced intracellular calcium mobilization incubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProteinase-activated receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50386404(CHEMBL1332325)
Affinity DataIC50:  3.30E+3nMAssay Description:Antagonist activity at PAR1 in human EAhy926 cells assessed as inhibition of TFLLRN-NH2-induced intracellular calcium mobilization pretreated for 15 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProteinase-activated receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50386404(CHEMBL1332325)
Affinity DataIC50:  3.16E+3nMAssay Description:Antagonist activity at PAR1 in human EAhy926 cells assessed as inhibition of TFLLRN-NH2-induced intracellular calcium mobilization pretreated for 15 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed