BDBM50386646 CHEMBL2048622

SMILES CCS(=O)(=O)CCOc1cc(C)c(c(C)c1)-c1cccc(COc2ccc(CCC(O)=O)c(F)c2)c1

InChI Key InChIKey=HUBPXUHEJRXYHI-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50386646   

TargetFree fatty acid receptor 1(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50386646(CHEMBL2048622)
Affinity DataKi:  4.20nMAssay Description:Displacement of 3-[4-({2',6'-dimethyl-6-[(4-[3H])phenylmethoxy]biphenyl-3-yl}methoxy)phenyl] propanoic acid from rat GPR40 receptor expressed in CHO ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFree fatty acid receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50386646(CHEMBL2048622)
Affinity DataKi:  15nMAssay Description:Displacement of 3-[4-({2',6'-dimethyl-6-[(4-[3H])phenylmethoxy]biphenyl-3-yl}methoxy)phenyl] propanoic acid from human GPR40 receptor expressed in CH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFree fatty acid receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50386646(CHEMBL2048622)
Affinity DataEC50:  25nMAssay Description:Agonist activity at human GPR40 receptor expressed in CHO cells assessed as increase in intracellular calcium level for 90 secs by FLIPR assay in the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed