BDBM50386769 CHEMBL2046910

SMILES Nc1nc2n(c[n+](CCOc3ccc(Cl)c(F)c3)c2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]1O

InChI Key InChIKey=OSDHZJVAKUMRCL-LSCFUAHRSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50386769   

LigandPNGBDBM50386769(CHEMBL2046910)
Affinity DataIC50:  2.65E+3nMAssay Description:Inhibition of eIF4E in rabbit reticulocyte cell lysate assessed as inhibition of cap-dependent translation after 90 mins by luciferase reporter gene ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50386769(CHEMBL2046910)
Affinity DataIC50:  56nMAssay Description:Competitive inhibition of [3H]m7-GTP binding to human FLAG-His6 tagged eIF4E expressed in Escherichia coli by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed