BDBM50387882 CHEMBL2057800

SMILES CN1CCN(CC1)c1nc(C)nc2n(C3CC3)c(nc12)-c1ccccc1Cl

InChI Key InChIKey=ATTXJDZGDVZJEP-UHFFFAOYSA-N

Data  2 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50387882   

TargetCannabinoid receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50387882(CHEMBL2057800)
Affinity DataEC50:  4.10nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cells assessed as [35S]-GTPgammaS binding preincubated for 25 mins measured after 30 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50387882(CHEMBL2057800)
Affinity DataEC50:  4.10nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cells assessed as stimulation of [35S]GTPgamma binding after 30 mins by scintillation proximi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50387882(CHEMBL2057800)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]-CP-55940 from human CB2 receptor expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50387882(CHEMBL2057800)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-CP-55940 from rat CB2 receptor expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50387882(CHEMBL2057800)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cells assessed as [35S]-GTPgammaS binding preincubated for 25 mins measured after 30 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50387882(CHEMBL2057800)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human CB1 receptor expressed in Sf9 cells assessed as stimulation of [35S]GTPgamma binding incubated for 15 mins prior to [35S]GT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed