BDBM50388921 CHEMBL2063281

SMILES Cc1ccc(NC(=O)c2ccc3nc([nH]c3c2)-c2c(C)cc(OCC(O)=O)cc2C)cc1C

InChI Key InChIKey=SNTCIFKVANLNAU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50388921   

TargetDiacylglycerol O-acyltransferase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50388921(CHEMBL2063281)
Affinity DataIC50: 28nMAssay Description:Inhibition of human recombinant His6-tagged DGAT1 expressed in insect Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50388921(CHEMBL2063281)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DGAT1 in mouse C2C12 cells assessed as reduction in triglyceride synthesis after 2 hrs by LC/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed